Roles of Glutamate Receptors and the Mtor Signaling Pathway in Activity-dependent Dendritic Protein Synthesis in Hipocampal Neurons*
نویسندگان
چکیده
IN ACTIVITY-DEPENDENT DENDRITIC PROTEIN SYNTHESIS IN HIPOCAMPAL NEURONS* Ruomu Gong, Chang Sin Park, Nima Rezaei Abbassi and Shao-Jun Tang From the Department of Neurobiology and Behavior, Center for Neurobiology of Learning and Memory, University of California, Irvine, CA 92697-3800, USA Running Title: Glutamate Receptors and the mTOR Signaling in Dendritic Protein Synthesis Address Correspondence to: Shao-Jun Tang, 303 Qureshey Research Laboratory, Center for Neurobiology of Learning and Memory, University of California, Irvine, CA 92697-3800, USA, Tel: (949)824-9580; Fax: (949)824-9762; Email: [email protected]
منابع مشابه
Roles of glutamate receptors and the mammalian target of rapamycin (mTOR) signaling pathway in activity-dependent dendritic protein synthesis in hippocampal neurons.
Local protein synthesis in neuronal dendrites is critical for synaptic plasticity. However, the signaling cascades that couple synaptic activation to dendritic protein synthesis remain elusive. The purpose of this study is to determine the role of glutamate receptors and the mammalian target of rapamycin (mTOR) signaling in regulating dendritic protein synthesis in live neurons. We first charac...
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